£6m statin trial raises hope drug can be used to treat multiple sclerosis : The Guardian

SUBSTRATUMS

Trial involving almost 1,200 people aims to ‘establish definitively’ whether cholesterol drug can slow disability progression.

Scientists are hopeful a major drug trial will establish that statins can be used to treat multiple sclerosis.

The low-cost drugs are typically prescribed to help lower levels of “bad cholesterol” associated with raised risk of a heart attack or stroke, but they have also shown “incredible promise” for the treatment of MS.

A small study – involving 140 people – published in the Lancet in 2014 on patients with secondary progressive MS, found those taking high doses of simvastatin had a significant reduction in the rate of brain atrophy over two years and also had better disability scores at the end of study.

The new trial will be much larger, involving 1,180 people, and will aim to establish whether the drug can slow disability progression. The £6m project has funding from the National…

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