Regular low doses of THC dramatically boosted memory and learning in older mice, say scientists, who plan a clinical trial in humans later this year.
Researchers have come up with an unusual proposal to slow, or even reverse, the cognitive decline that comes with old age: small, daily doses of cannabis extract.
The idea emerged from tests on mice which found that regular, low doses of tetrahydrocannabinol (THC) – the main psychoactive ingredient in cannabis – impaired memory and learning in young animals, but boosted the performance of old ones.
The discovery has raised hopes for a treatment that improves brain function in old age without inducing the behavioural effects well known to recreational users of the drug. To investigate whether it works in humans, the scientists plan to launch a clinical trial later this year.
“If we can rejuvenate the brain so that everybody gets five to 10 more…
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